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May 25, 2021 at 04:30PM The United Kingdom didn’t think much about particles or waves or quantum nonsense when it blew up Helgoland in 1947. It only knew that there were thousands of tons of World War II armaments to dispose of and the little island in the North Sea made a perfect place. The explosion was the largest non-nuclear blast of its time, and it came just 22 years after a much smaller, quieter detonation took place on the same island—when a young German physicist named Werner Heisenberg completed the equations that provided humanity’s first glimpse into the hallucinatory world of quantum physics. Close to a century later, that early revelation is being explained with uncanny insight and lyrical grace by best-selling author and theoretical physicist Carlo Rovelli, in his latest book, aptly named Helgoland . Rovelli explores such head-spinning notions as the reason observing an event determines its outcome, why time doesn’t really exist, and how it feels to devote yo

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May 24, 2021 at 08:45PM The darkness descends slowly for people with retinitis pigmentosa (RP), a degenerative eye disease that affects 2 million people worldwide. The condition is typically diagnosed in childhood or adolescence, but it can take until middle age before a person’s vision has deteriorated severely enough that they are fully or effectively blind. When the lights finally do go out, however, they stay out. Or that’s the way things used to be. In a breakthrough study published today in Nature Medicine , investigators report a relatively simple yet remarkably effective way to restore partial vision to RP patients—one that, with further study, may soon have wide application. The key lies in the rod-shaped photoreceptors that principally govern peripheral vision and the cone-shaped receptors that give us our central view of the world. In people with RP, mutations in more than 70 genes cause slow deterioration of the rods, leading to tunnel vision, and later the c

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May 17, 2021 at 10:50PM A version of this article also appeared in the It’s Not Just You newsletter. Sign up here to receive a new edition every Sunday. This week, we have a special Mental Health Awareness Month edition of It’s Not Just You. In addition to the piece below, you can read a guest essay from Ciara Alyse Harris , one of the stars of the hit Broadway show, Dear Evan Hansen here. My dad, who was always intuitive, told us he saw that my little sister’s depression had returned when he printed photographs he’d taken of her. “I could see it in her eyes, like a ghost,” he said. It was an observation born of love and experience, not science, but not wrong. Until recently, major depression has felt like a ghost disease–invisible but devastating. It’s a disorder that still affects millions every year–one in four of us will suffer a depressive episode in their lifetime. Despite those numbers and the fact that humans have been documenting and speculating about it fo

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